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Tim Thompson has been a member since May 14th 2011, and has created 566 posts from scratch.

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Mice with Alzheimer’s Should Not Drink Coffee

We have reported numerous health benefits from drinking coffee. Included in our reports was one entitled Forget Your Alzheimer’s and Drink Your Coffee.

Research carried out at the University of South Florida implies that it may be time to forget your Alzheimer’s and drink your coffee. Alzheimer’s disease is the condition seen often in old age in which a person is unable to remember recent events. It is also the stuff of jokes about every time a person in mid-life or older forgets something.

The scientists at South Florida studied a strain of mice that has been bred to get Alzheimer’s disease, or at least the mouse variety. These critters develop high levels of beta amyloid in their brain and then the plaques inhibit nerve transmission. These are the same findings that researchers see in humans. Because mice live shorter lives than humans, old age comes sooner. Thus scientists can see sooner if whatever they have been doing to the mice has had an effect. Now these folks have been having their little research subjects drink coffee.


The result of that study was this.

Coffee is a natural for this purpose. Caffeine and something else in coffee reliably reduce beta amyloid levels in the brain of mice.

That is to say the damaging plaques that seem to lead to the Alzheimer’s equivalent in mice are reduced by drinking coffee.

So, if drinking coffee is likely to reduce the precursors of Alzheimer’s we should drink coffee. Right?

But, now researchers have studied mice that already have the mouse equivalent of Alzheimer’s. And they have found that consuming the equivalent of what would be 5 cups of coffee a day worsens symptoms in the rodents.

And, if grandpa already has Alzheimer’s he should not drink coffee. Right?

Applying Mouse Research to Humans

Is it a valid assumption that what applies to mice will apply to humans as well? To make sense of this we looked online at an article in Science: How Things Work.

The mouse’s DNA looks startlingly like ours; in fact, we share more than 90 percent of the same genes as a mouse.

But dogs and pigs are more closely related to us. But people are uncomfortable sacrificing large numbers of these animals in the name of science.

Mice might not be the closest animals to us genetically, but they are one of the closest that we feel comfortable using in studies.

And mice mature faster so that researchers can test various treatments and get results in a year or two instead of waiting a dozen or more years in other animals of six to eight decades in humans.

As a practical matter mice are easier to study and the studies produce quicker results. But, there is not a one to one correlation between people and rodents. Thus, it might provide useful insight to look at how mice with Alzheimer’s react to coffee but a more reliable way to test this is to give Grandpa a cup of coffee or two and see how he does. In the case of drinking coffee the results are virtually immediate so the mice do not give us anything useful in terms of an early result.

Organic Coffee: No Caffeine

There is really only one organic coffee without caffeine and that is made using the Swiss Water method. People have been removing caffeine from coffee for decades. The earliest methods are still used these are the direct and indirect solvent methods. They get the caffeine out of the coffee but are not organic methods.

Indirect Solvent Method

Coffee beans are soaked for several hours in hot water just below the boiling point. This removes caffeine but also other chemicals that give coffee its flavor and aroma.

Then the water is drawn off to another container and where a solvent is added. The solvent binds to the caffeine. Then the mixture is re-heated the caffeine and volatile solvent combination evaporates. When the beans are added to the remaining mixture, they reabsorb the remaining chemicals and regain some of the coffee flavor.

Direct Solvent Method

In the direct solvent method coffee beans are steamed for about half an hour. For the next ten hours they are repeatedly rinsed with the solvent. Finally, the solvent is drained off and the beans are steamed one las time.

Neither of these methods qualifies as organic.

CO2 Method

This is a non-solvent means of decaffeinating coffee. It works for very large batches and is used for regular coffee in a huge scale. The problem is that the process is very expensive and is only economical when used on a large scale.

Coffee beans are put under pressure of 1,000 pounds per square inch with liquid carbon dioxide in a stainless steel tank. The CO2 dissolves the caffeine and leaves the other coffee constituents alone. When the CO2 is removed from the tank it passes briefly though a gas phase when it loses its caffeine and can be used again.

This process qualifies as organic but is too expensive to use except for huge batches of regular coffee.

Swiss Water Method

This is an organic method to decaffeinate coffee and is certified as such. It is also applicable to reasonable batch sizes making it appropriate for organic coffee.

This means of decaffeination was discovered 80 years ago but has only be in use for about 30 as it required adjustments to make it cost effective.

Caffeine is removed from coffee beans with hot water. The hot water is passed through a large pore activated charcoal filter which traps the caffeine but allows smaller antioxidant and other molecules to pass through.

Then new beans are soaked with the caffeine poor but antioxidant rich water. Via osmosis caffeine leaves the beans while antioxidants remain. This process provides a coffee that is 99.95% caffeine free and is certified as such. Swiss Water decaf is labeled as such and is the only commercially available organic coffee without caffeine.

Unfortunately, there is no good way to decaffeinate coffee at home so you cannot purchase your favorite coffee and then remove the caffeine. But you can buy Arabica coffee which is lower in caffeine than Robusta and you can buy organic coffee from Colombia.

How Does Coffee Block the Effects of Marijuana?

We have commented on many scientific studies relating to the health effects of drinking coffee. However, the bulk of these studies use reported coffee intake and reported health results. They are associative studies and do not get to the mechanics of how coffee with its antioxidants and caffeine may be helping people live longer, have better sex, or improve athletic performance. This may be about to change. Researchers at Northwestern University have been looking deeply into the metabolic effects of drinking coffee. Live Science reports on a study published in the Journal of Internal Medicine and comments that coffee could be the opposite of cannabis. In short, how does coffee block the effects of marijuana?

According to a new study, your morning Joe causes a drop in the levels of certain substances that are linked to the body’s system for responding to marijuana.

The levels of these substances – metabolites found in what’s known as the endocannabinoid system – decrease in people who drink between four and eight cups of coffee a day, according to the study, published today (March 15) in the Journal of Internal Medicine. Endocannabinoids are molecules that bind to cannabinoid receptors, which are found all over the nervous system, as well as in immune and endocrine tissue. The body makes its own endocannabinoids, but it also responds to foreign cannabinoids, like the ones found in the leaves of plants of the Cannabis genus.

How Does Coffee Block the Effects of Marijuana?

It would appear that drinking coffee hastens the breakdown of metabolites of cannabis. Thus, coffee blocks the effects of marijuana by getting rid of it faster from the body.

In addition, the study noted effects of coffee on steroid metabolites as well and the author commented on how these effects may help explain how coffee affects the incidence of Type II diabetes and various kinds of cancer.

Do You Really Need to Understand the Science to Enjoy and Benefit from the Coffee?

When you start your car in the morning you really do not want to have to worry about or understand the function of every piece of equipment under the hood. And when you make your morning coffee or buy a cup at the coffee house you do not need to understand the metabolic results of drinking your cup of Java.

The value of the associative studies that we have reported is that they tell you what the bottom line is. Which is to say, if you drink coffee you will probably live longer than if you do not. If you drink coffee the benefits are more pronounced if you are more than 50 years old. And, there are a whole host of bad diseases which you will be less likely to get if you are a coffee drinker, with the best benefits being in the four to six cups a day range.

What Do You Do?

Coffee is good for you. And the science is getter to explain jus why that is. In the meantime, drink Arabica organic coffee instead of regular in order to avoid the more than 100 impurities that may be found in regular coffee. And the best Arabica coffee, organic or not, typically comes from Colombia. Check with us at Buy Organic Coffee for the details.

What Is Honest Organic Coffee?

There is a new name on the bottled cold brewed coffee scene. The largest seller of soft drinks and other non-alcoholic beverage in the world, Coca Cola, is marketing a product called Honest Organic Coffee. If you are interested in bottled cold brewed coffee to go this might be a good choice.

A refreshing summer drink is cold brewed coffee. Cold brewed coffee is about two thirds less acidic than espresso or percolator coffee. It has to do with extracting caffeine and healthy antioxidants but less acid using a slow, cool extraction process. Basically the coffee just diffuses out of the ground beans over a few hours. And now, if you do not want to spend the time making your own cold brew coffee, you can buy bottled cold brew coffee and store it in your frig!

But, it turns out that while Honest Organic Coffee is really organic it is coffee that has been brewed, canned and cooled. It is not necessarily cold brewed coffee. Nevertheless, the organic part addresses one of our concerns about bottled or canned coffee.

Bottled cold brew coffee sounds interesting but if you like the idea of healthy organic coffee is the cold brewed bottled coffee organic? And how to the organic coffee antioxidants preserve in a bottle?

Coca Cola is launching the Honest Organic Coffee brand in Great Britain with not just plain coffee but bottled coffee house coffee as well. The trade publication Packaging News reports on Coca Cola’s launch of cold coffee drinks.

Launching in March, there will be two great tasting variants in the organic Honest Coffee range – Latte and Mocha. The product range will tap into the growing consumer demand for RTD coffee products in GB, a sector which is worth £66m and growing by 20% year on year.

The coffee drinks will be available in a re-sealable 240ml single PET, designed to suit consumers with an on-the-go lifestyle – with workplace and higher education among the key channels for the product. Made with Arabica beans, the products are organic and exempt from the soft drinks tax that comes into effect in April. The 42.5% coffee content and lower sugar delivers a taste profile that is less sweet than some RTD coffee options, appealing to consumers who want a more authentic cold coffee experience.

The appeal of cold coffee is that you can simply go to your refrigerator and take out a can or bottle instead of having to go to the coffee shop and stand in line or wait in your car for drive up service. And, of course, there are no issues with hot coffee burns for which Starbucks had to pay a customer.

And when buying coffee house coffee you should also be aware of how hot it might be and if the lid is on tight when you buy for takeout.

A Florida woman who was severely burned after the lid popped off a cup of Starbucks coffee and spilled on her lap was awarded $100,000 for her injuries Thursday.

A Starbucks representative testified during the trial that the coffee company receives 80 complaints a month about issues with lids popping off or leaking.

In our article how, How Hot Is Starbucks Coffee, we cited expert opinion about hot coffee and burns. The Burn Foundation discusses hot liquid burns.

When tap water reaches 140º F, it can cause a third degree (full thickness) burn in just five seconds.

Hot Water Causes Third Degree Burns

in 1 second at 156º

in 2 seconds at 149º

in 5 seconds at 140º

in 15 seconds at 133º

How hot is Starbucks coffee? If the lady actually suffered 3rd degree burns the coffee was probably at least 140 degrees and more likely 150 or above.

That is the argument for products like Honest Organic Coffee instead of takeout at Starbucks or McDonalds.

Organic Coffee for Sale

Where can you find organic coffee for sale and how can you know that it is high quality and fresh? The best organic coffee comes from places like Colombia. Arabica coffee is the gold standard for quality but you also want fresh beans and not ones that were in storage for years. And to make sure that your Arabica coffee is organic look for proof of organic coffee certification on the bag.

Organic coffee differs from regular coffee in several aspects. The soil in which organic coffee is grown must have been verified as free from prohibited substances for at least three years. In addition there must be distinct boundaries between land on which organic coffee is grown and land where pesticides, herbicides, and prohibited chemical fertilizers are used. This guarantees that drift of substances sprayed or otherwise applied on adjacent land will not contaminate the organic plot of land. Organic coffee certification includes the adherence to a specific and verifiable plan for all practices and procedures from planting to crop maintenance, to harvest, de-husking, bagging, transport, roasting, packaging, and final transport. Along the way procedures must be in place at every step to insure that there is no contamination of the healthy organic coffee produced in pristine soil with regular coffee produced on soil exposed to herbicides, pesticides, and organic fertilizers.

There are many great coffees grown by organic methods but your only proof of organic content is the USDA, UTZ or Rainforest Alliance seal on the bag. That means someone visited the coffee farm and checked to make sure the farmer was following set guidelines.

Old versus Fresh

A few years ago coffee farmers in Brazil put coffee beans into storage rather than sell them because prices were so low. Then, after a few years, coffee prices went up and coffee farmers sold every bean that they had. Unfortunately, a lot of that old coffee was only good for sale to institutional buyers. In our recent article about organic coffee with the most antioxidants we wrote about the importance of coffee freshness.

And, before that, we wrote about how to get freshly roasted Colombian coffee.

Buy Organic Coffee to the Rescue

If you would like coffee that was just picked and processed and has been roasted within the last week or so contact us at BuyOrganicCoffee.org. We work with coffee roasters in places like Manizales or Chinchina in the heart of the Eje Cafetero. Order your coffee and we will have our partners select the freshest coffee beans, roast them to perfection, and send to your via express air delivery. That is how you can get freshly roasted Colombian coffee.

If you want the best organic coffee for sale, send us a message at BuyOrganicCoffee.org. We will be pleased to find the best organic coffee for sale in Colombia where they grow the best coffee. And then we will arrange to have that great organic or otherwise great Colombian coffee sent directly to you whether you are interested in green coffee beans or recently roasted.